发明名称 |
Yeast cells having mutations in stp22 and uses therefor |
摘要 |
The invention provides yeast cells which comprise a mutation in an endogenous yeast stp22 gene and which express a heterologous G protein coupled receptor. The instant yeast cells display enhanced sensitivity to ligand induced stimulation of heterologous G protein coupled receptors and, therefore, show improved properties in drug screening assays.
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申请公布号 |
US6355473(B1) |
申请公布日期 |
2002.03.12 |
申请号 |
US19990305923 |
申请日期 |
1999.05.05 |
申请人 |
CADUS PHARMACEUTICAL CORP. |
发明人 |
OSTANIN KIRILL;SILVERMAN LAUREN |
分类号 |
C07K14/39;C07K14/72;G01N33/566;(IPC1-7):C12N1/14;C07H21/04;C07K1/00 |
主分类号 |
C07K14/39 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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