发明名称 |
Antisense inhibition of integrin beta 4 binding protein expression |
摘要 |
Antisense compounds, compositions and methods are provided for modulating the expression of Integrin beta 4 binding protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Integrin beta 4 binding protein. Methods of using these compounds for modulation of Integrin beta 4 binding protein expression and for treatment of diseases associated with expression of Integrin beta 4 binding protein are provided.
|
申请公布号 |
US6355482(B1) |
申请公布日期 |
2002.03.12 |
申请号 |
US20000716161 |
申请日期 |
2000.11.17 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
BENNETT C. FRANK;FREIER SUSAN M. |
分类号 |
A61K38/00;C12N15/113;(IPC1-7):C07H21/04;C07H21/02;C12N15/85;C12N15/86;C12P19/34 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|