| 摘要 |
The present invention describes a system and method to improve radiation delivery through a barrier that may be encountered during therapeutic laser procedures, particularly where the objective of treatment is to produce thermal damage or alterations to subsurface tissue constituents without destroying or altering the overlying barrier. To achieve this result, a bio-compatible fluid is preoperatively administered to the tissue. The bio-compatible fluid is a light-scattering fluid that will scatter light primarily at the desired site thereby achieving a more uniform, enhanced heating over a relatively large treatment area. In addition, a second fluid, a dispersion fluid, can be added to the tissue to function in distributing the light scattering fluid throughout the treatment site. Laser radiation is then administered, through micro pores created for example by a device such as a micro-needle patch, into the treatment site. When a micro-needle patch is employed to deliver the fluid and the radiation, it can be a single patch for both functions, or a separate patch for each function.
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