发明名称 |
LIQUID INJECTABLE FORMULATION OF DISODIUM PAMIDRONATE |
摘要 |
The present invention relates to an improved injectable ready to use preparation of pamidronate salts, methods for its manufacture and uses of the solution o f the invention in the manufacture of pharmaceutical compositions for the treatment of diseases selected from the group of tumour-induced hypercalcaemia, Paget's disease, osteoporosis, bone metastases, or breast cancer. The ready to use solution comprises a physiologically acceptable alkaline salt which is water soluble and a physiologically acceptable aqueou s solvent having a concentration of between 0.1 and 100 mg/mL which has not been reconstituted from a lyophilizate, wherein the solution is provided in a sealed non-reactive container. |
申请公布号 |
CA2347330(C) |
申请公布日期 |
2002.03.12 |
申请号 |
CA20012347330 |
申请日期 |
2001.05.10 |
申请人 |
PHARMACEUTICAL PARTNERS OF CANADA INC. |
发明人 |
HAHN, SAM;SZYMANSKI, DENNIS |
分类号 |
A61K9/00;A61K9/08;A61K31/663;A61K47/02;A61K47/26;A61P19/08;A61P19/10;A61P35/04 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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