发明名称 Topical application of antibodies for contraception and for prophylaxis against sexually transmitted diseases
摘要 Certain antibody molecules are so stable and so potent at immobilizing sperm as well as the pathogens for sexually transmitted diseases (STDs) that they make possible new prophylactic contraceptive methods: (a) for men, a skin lotion containing antibodies against sperm and against STD pathogens to be applied to the penis and external genitals during sexual activity, thereby delivering prophylactically effective doses of antibodies to virtually all areas of skin and epithelia across which most STDs, including AIDS, are usually transmitted, and, during vaginal intercourse, the penis will deliver a contraceptively reliable dose of the antibodies to the cervical region of the vagina; and (b) for women, intrauterine devices (IUDs) and intravaginal devices (IVDS) that release antibodies into the uterus or into the vagina to provide continuous protection against pregnancy and STDs for periods of months to years.
申请公布号 US6355235(B1) 申请公布日期 2002.03.12
申请号 US19990447411 申请日期 1999.11.23
申请人 JOHNS HOPKINS UNIVERSITY 发明人 CONE RICHARD A.;WHALEY KEVIN J.
分类号 C07K16/00;(IPC1-7):A61K31/74;A61K39/395;A61K39/00;A61K39/40 主分类号 C07K16/00
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