发明名称 Steroid Sulphatase Inhibitors
摘要 1. Technical Result Widening of assortment of the means for treating oestrone dependent tumors. 2. Essence New inhibitors representing sulphamate esters of formula (I) wherein R1 and R2 are each H, alkyl, alkenyl, cycloalkyl or aryl, or together represent an alkylene group optionally containing a heteroatom e.g. -O- or -NH-; and -O- polycycle represents the residue of a polycyclic alcohol such as a sterol, preferably sterol. Preferable compounds oestron-3-sulfamate, N,N-dimethyl oestron-3- sulfamate. 3. Field of Application Medicine.
申请公布号 GEP20022802(B) 申请公布日期 2002.03.11
申请号 GE1992AP03991 申请日期 1992.08.28
申请人 STERIX LIMITED 发明人 REED, MICHAEL, J.;POTTER L., BARRY V.
分类号 A61K31/565;A61K31/00;A61K31/145;A61K31/56;A61K31/566;A61K31/567;A61K31/5685;A61P5/30;A61P5/32;A61P5/36;A61P35/00;A61P43/00;C07C307/02;C07J1/00;C07J31/00;C07J41/00;C07J43/00;C12N9/16 主分类号 A61K31/565
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