| 摘要 |
<p>The invention relates to methods and systems (108, 108a, 108b, 108c) for high-speed precision dispensing and/or aspirating of microfluidic quantities of reagents (130) and other liquids. The operation of the systems (108, 108a, 108b, 108c) is controlled by data accessed from a customized user-defined text file (520). Advantageously, the use of such text file control allows high-speed precision dispensing of one or more reagents (130) with a wide dynamic range of dispense volumes in complex combinatorial patterns, ratios and arrays onto or into multiple predetermined locations of a desired target or substrate (111). This is particularly advantageous when a large number of permutations of different reagents and permutations of reagent volume ratios are involved. The systems (108, 108a, 108b, 108c) may be operated in a high frequency modulated mode to further improve accuracy and reliability.</p> |
