发明名称 QUINOLINE-(C=O)-(DI-,TRI- AND TETRAPEPTIDE) DERIVATIVES AS CASPASE INHIBITORS
摘要 This invention concerns compounds and a pharmaceutical composition of the structure wherein: (I) R2 is selected from the group consisting of F and and (II) m is 1, 2 or 3. These compounds are reagents and pharmaceutical compositions have pro-drug and apoptosis properties and are useful in a variety of therapies, for diseases such as arthritis, ALS, MS.
申请公布号 CA2420667(A1) 申请公布日期 2002.03.07
申请号 CA20012420667 申请日期 2001.08.24
申请人 ENZYME SYSTEMS PRODUCTS, INC. 发明人 WANG, JINHAI
分类号 C12N9/99;A61K38/00;A61P1/00;A61P1/16;A61P1/18;A61P9/00;A61P9/10;A61P11/00;A61P13/12;A61P17/14;A61P19/02;A61P19/08;A61P25/00;A61P25/16;A61P25/28;A61P29/00;A61P31/00;A61P31/04;A61P31/18;A61P37/00;A61P37/06;A61P43/00;C07K5/06;C07K5/08;C07K5/093;C07K5/10;C07K7/06;(IPC1-7):C07D215/48;A61K31/198;A61K31/47;C07D209/16;C07D209/24;C07D405/12;C07K5/023 主分类号 C12N9/99
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