NUCLEIC ACID CONSTRUCTS INCLUDING A NOVEL T-CELL ACTIVE PROMOTER, AND PHARMACEUTICAL COMPOSITIONS AND METHODS UTILIZING SAME FOR REGULATING T-CELL MEDIATED IMMUNE RESPONSE

摘要

An isolated nucleic acid is disclosed, including a promoter sequence being transcriptionally functional in a T-lymphocyte undergoing activation and transcriptionally less functional in the T-lymphocyte prior to the activatio n.