METHODS AND COMPOSITIONS FOR INHIBITING ANGIOGENESIS
摘要
Methods for inhibiting angiogenesis in endothelial cells and selectively inducing apoptosis in endothelial cells via compounds which binds annexin II are provided. These compounds and methods for using these compounds are useful in the treatment of diseases or disorders characterized by unwanted angiogenesis. Also provided are pharmaceutical compositions containing a compound which binds annexin II and a pharmaceutically acceptable vehicle and methods for identifying such compounds.
申请公布号
WO0217857(A2)
申请公布日期
2002.03.07
申请号
WO2001US27310
申请日期
2001.09.04
申请人
PHILADELPHIA, HEALTH AND EDUCATION CORPORATION;SHARMA, MAHESH, C.;TUSZYNSKI, GEORGE, P.