发明名称 |
NOVEL ESTER OR AMIDE DERIVATIVES |
摘要 |
Ester or amide derivatives represented by the following general formula (I) which have an antibacterial effect on <i>Helicobacter pylori</i> or pharmaceutically acceptable salts thereof. In particular, ester or amide derivatives of 3-alkyl-3-oxo-1,4-dihydroquinoline-2-carboxylic acids represented by the following general formulae (I') and (I") or pharmaceutically acceptable salts thereof. In said formula (I), X<1> to X<4> independently represent each C or N; Y represents O or NH; R<1> represents C<1> to C<6> alkyl; R<2> represents C<1> to C<10> alkyl, etc.; R<3> represents hydrogen, C<1> to C<6> alkyl, etc.; and R<4> to R<7> are the same or different and each represents hydrogen, halogeno, C<1> to C<6> alkyl, etc.
|
申请公布号 |
WO0218344(A1) |
申请公布日期 |
2002.03.07 |
申请号 |
WO2001JP07307 |
申请日期 |
2001.08.27 |
申请人 |
YAMANOUCHI PHARMACEUTICAL CO., LTD.;KAZAMI, JUN-ICHI;WATANABE, MASATO;HIRATA, TAKUYA |
发明人 |
KAZAMI, JUN-ICHI;WATANABE, MASATO;HIRATA, TAKUYA |
分类号 |
A61K31/4375;A61K31/44;A61K31/47;A61K31/4709;A61K31/4741;A61K31/503;A61K31/519;A61K31/5383;A61P31/04;C07D215/36;C07D215/48;C07D401/14;C07D471/02;C07D471/04;C07D471/14;C07D487/02;C07D498/06;(IPC1-7):C07D215/48;A61K31/470;A61K31/437;A61K31/538 |
主分类号 |
A61K31/4375 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|