METHOD AND APPARATUS FOR IMPRESSING A MASTER PATTERN TO A GEL IMAGE

摘要

A computer-implemented method analyzes a scanned image of a 2-D electrophoresis gel producing spot specific data (SSD). The computer create an object pattern in order to warp a master pattern into alignment with the object pattern (and hence the scanned patter) (S2). The object pattern is replaced with the warped master pattern (S7), augmented by addition of well defined spots in the object image not present in the warped master pattern (S8), and optimized to fit a processed version of the scanned image (S9). This new object model thus contain identifying and relative position information from the master pattern and other spot specific data (SSD) from the old object model. The new object Pattern thereby forms a basis upon which to compare the scanned image with other scanned images similarly processed.