PROCESS FOR PREPARATION OF HYDRATES OF OLANZAPINE AND THEIR CONVERSION INTO CRYSTALLINE FORMS OF OLANZAPINE
摘要
<p>The present invention relates to a method for the preparation of hydrates of 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno [2,3-b] [1,5] benzodiazepine (hereinafter referred to as Olanzapine). The present invention also relates to a process for conversion of these hydrates into a pure crystalline form of olanzapine referred to as form-I. The present invention also relates to a method of converting Olanzapine Form-2 to Form-1.</p>
申请公布号
WO0218390(A1)
申请公布日期
2002.03.07
申请号
WO2001US07258
申请日期
2001.03.07
申请人
DR. REDDY'S LABORATORIES LTD.;KOPROWSKI, ROBERT;REGURI, BUCHI, REDDY;CHAKKA, RAMESH