发明名称 |
PROCESS FOR THE PREPARATION OF PHENYLPHENOL COMPOUNDS |
摘要 |
There is described the preparation of phenylphenol compounds of formula (1) by reaction of a keto compound of formula (3) with dioxolane of formula (4) and with an ammonium compound of formula (5) to form a beta -aminoketone compound of formula (6) (reaction step (I)), reaction of the compound of formula (6) with a compound of formula (7) to form a compound of formula (2) (reaction step (II)), and subsequent alkylation to form a compound of formula (1) (reaction step (III)) in accordance with scheme (A); wherein R1, R2, R3, R6 and R7 are each independently of the others hydrogen or C1-C8alkyl; R4, R5 and R8 are each independently of the others hydrogen or C1-C5alkyl; and Hal is a halogen atom. The compounds prepared in accordance with the invention are suitable as antimicrobial active substances.
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申请公布号 |
WO0218311(A1) |
申请公布日期 |
2002.03.07 |
申请号 |
WO2001EP09666 |
申请日期 |
2001.08.21 |
申请人 |
CIBA SPECIALTY CHEMICALS HOLDING INC.;NUSSBAUM, KLAUS;HOFFMANN, MARTINA |
发明人 |
NUSSBAUM, KLAUS;HOFFMANN, MARTINA |
分类号 |
A01N31/08;A61P31/00;C07C39/15;C11D3/00;C11D3/20;C11D3/48;C11D9/50;D06M13/152;D06M16/00;D21H21/36;(IPC1-7):C07C39/15;A61K7/40;A61K7/075;A61K7/32 |
主分类号 |
A01N31/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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