Ceftiofur, its intermediate and a process for the preparation of the same

摘要

A novel process for the preparation of ceftiofur, a cephalosporin antibiotic useful in the treatment of bovine respiratory disease. The process utilizes a new bromo or chloro intermediate that can be isolated in a pure form by this inventive process subsequently resulting in ceftiofur of high purity. This invention offers a new-to-the-world route to Ceftiofur using novel intermediates.