发明名称 |
Genetic marker test for lupus |
摘要 |
Disclosed is a genetic testing method for diagnosing systemic lupus erythematosus (SLE) in a human subject. The method is related to amplifying nucleic acids from human tissue samples and analyzing for a variant allele of a gene encoding poly(ADP-ribosyl)transferase expression (<I>PARP</I>), which is diagnostic of SLE or indicates a genetic predisposition for developing SLE. Also disclosed are useful oligonuclotide primers, primer sets and genetic testing kits for detecting a genetic predisposition for developing SLE.
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申请公布号 |
GB2366378(A) |
申请公布日期 |
2002.03.06 |
申请号 |
GB20010023514 |
申请日期 |
2000.03.28 |
申请人 |
* CEDARS-SINAI MEDICAL CENTER;BETTY PEITIE * TSAO |
发明人 |
BETTY PEITIE * TSAO;RITA M * CANTOR;JEROME I * ROTTER |
分类号 |
C07H21/04;C12P19/34;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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