| 发明名称 |
METHODS FOR REGULATING PROTEIN CONFORMATION USING MOLECULAR CHAPERONES |
| 摘要 |
The present invention provides a method for regulating the confirmation of proteins using molecular chaperones. The chaperones of the present invention are applicable to a variety of protein conformational problems including misfolding and aggregation. A molecular chaperone system of the present invention includes the DnaK system and ClpB which provides a particularly effective tool for regulating protein conformation. A further subject of the present invention is a cochaperone ClpS. |
| 申请公布号 |
EP1183363(A2) |
申请公布日期 |
2002.03.06 |
| 申请号 |
EP20000925293 |
申请日期 |
2000.05.18 |
| 申请人 |
ROCHE DIAGNOSTICS GMBH;BUKAU, BERND |
发明人 |
BUKAU, BERND;GOLOUBINOFF, PIERRE |
| 分类号 |
A01K67/027;A01K67/033;A61K31/7088;A61K35/76;A61K38/00;A61K39/02;A61K48/00;A61P25/02;A61P25/14;A61P25/28;A61P35/00;A61P43/00;C07K1/113;C07K14/00;C07K14/245;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/04;C12N15/09;C12N15/31;C12P21/02 |
主分类号 |
A01K67/027 |
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