Kinazoline derivater

摘要

The invention concerns quinazoline derivatives of Formula (I) wherein Q<1 >includes a quinazoline ring optionally substituted with a group such as halogeno, trifluoromethyl and cyano, or a group of the formula: Q<3>-X<1>- wherein X<1 >includes a direct bond and O and Q<3 >includes aryl, aryl-(1-6C)alkyl, heterocyclyl and heterocyclyl-(1-6C)alkyl; each of R<2 >and R<3 >is hydrogen or (1-6C)alkyl; Z includes O, S and NH; and Q<2 >includes aryl and aryl-(1-3C)alkyl or a pharmaceutically-acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the prevention or treatment of T cell mediated diseases or medical conditions in a warm-blooded animal.