发明名称 |
NEURON PROTECTOR AND MANUFACTURING METHOD THEREOF |
摘要 |
PURPOSE: Provided are a neuron protector which inhibits apoptosis induced by excitotoxicity such as NMDA, AMPA, kainate and the like, and its manufacturing method. CONSTITUTION: The neuron protector, complestatin, is manufactured by steps of: identifying and culturing Streptomycessp.60190 strain(KCTC 0843 BP) which produces a neuron protector; then extracting aromatic peptide complestatin, which is represented by the formula(I) and has apoptosis inhibiting and neuron protecting activities, therefrom.
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申请公布号 |
KR20020016279(A) |
申请公布日期 |
2002.03.04 |
申请号 |
KR20000049529 |
申请日期 |
2000.08.25 |
申请人 |
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY |
发明人 |
KWAK, BYEONG JU;YOO, IK DONG;YOO, IN JA;YOON, BONG SIK |
分类号 |
C12N1/20;A61K38/00;C07K7/06;C12P21/02;(IPC1-7):C12N1/20 |
主分类号 |
C12N1/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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