发明名称 DERIVADOS DE AMINOTERAZOLE UTEIS COMO INIBIDORES DA SINTASE DO OXIDO NITRICO
摘要 Compounds having formula (I) and pharmaceutically acceptable salts thereof, wherein B is NR<5>R<11>, wherein R<5> is selected from the group consisting of hydrogen, lower alkyl, lower alkenyl, lower alkynyl and aryl, and R<11> is selected from a 3 to 8 member heterocyclyl radical in which at least one member of the ring is carbon and in which 1 to about 4 members are heteroatoms independently selected from oxygen, nitrogen and sulfur and said heterocyclyl radical may be optionally substituted, useful as nitric oxide synthase inhibitors. <CHEM>
申请公布号 PT790987(E) 申请公布日期 2002.02.28
申请号 PT19950937674T 申请日期 1995.11.08
申请人 G.D. SEARLE & CO. 发明人 E. ANN HALLINAN;SOFYA TSYMBALOV;DONALD W. HANSEN, JR.
分类号 C12N9/99;A61K31/41;A61K31/415;A61K31/4168;A61K31/425;A61K31/426;A61K31/505;A61P9/00;A61P43/00;C07C257/14;C07D231/40;C07D233/88;C07D239/22;C07D239/42;C07D249/14;C07D257/06;C07D277/18;C07D277/20;C07D277/46;C07D277/50;(IPC1-7):C07D257/06 主分类号 C12N9/99
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