发明名称 USE OF CYCLIC 2,4-DIPHOSPHOGLYCERATES (CDGP) AND/OR DERIVATIVES THEREOF IN COSMETIC AND DERMATOLOGICAL FORMULATIONS
摘要 The invention relates to the inclusion of the low molecular weight substance (compatible solute), cyclic 2,4-diphosphoglycerate (cDGP), from extremophilic micro-organisms and/or derivatives of said compound, for example, an acid, a salt, or an ester, in cosmetic or dermatological formulations for protection of the skin from environmental influences and to increase the regeneration capacity. According to the invention, cyclic 2,4-diphosphoglycerate is implicated in active cell protection of the endogenous cell radical traps, antioxidants, the DNA, cell membranes and further cell compartments, by means of a protective effect of the above, against damaging environmental effects, for example, UV radiation, IR radiation, and environmental stress (thermal, chemical and physical). The compatible solute may serve as co-solvent and penetration improver for other active ingredients added to the cosmetic formulation, in order to not only stabilise the above in the cosmetic formulation, but also for active transport into deeper skin layers.
申请公布号 WO0215866(A2) 申请公布日期 2002.02.28
申请号 WO2001EP09443 申请日期 2001.08.16
申请人 BITOP GESELLSCHAFT FUER BIOTECHNISCHE OPTIMIERUNG MBH;SCHWARZ, THOMAS 发明人 SCHWARZ, THOMAS
分类号 A61K8/00;A61K8/14;A61K8/27;A61K8/37;A61K8/44;A61K8/49;A61K8/55;A61K8/58;A61K8/65;A61K8/67;A61K31/665;A61P17/16;A61P31/00;A61P31/12;A61Q1/00;A61Q1/04;A61Q1/06;A61Q1/10;A61Q1/12;A61Q5/00;A61Q17/00;A61Q17/04;A61Q19/00;A61Q19/10 主分类号 A61K8/00
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