摘要 |
It is intended to provide an IRAP (insulin responsive aminopeptidase)-binding protein, etc. More particularly speaking, an IRAP-binding protein, drugs containing this protein, a method of screening a compound inhibiting the binding of this protein to IRAP, compounds obtained by the screening method, etc. are provided. The above-described protein is useful as, for example, preventives and remedies for hypoglycemia. This protein is also useful as a reagent for screening a compound inhibiting the binding of the protein to IRAP or GLUT4 (glucose transporter 4). Compounds inhibiting the binding of this protein to IRAP or GLUT4 are useful as, for example, preventives and remedies for hyperglycemia, diabetes, etc. |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD.;TOJO, HIDEAKI;KATAYAMA, NOZOMU;KAKIMOTO, SHIGEYA |
发明人 |
TOJO, HIDEAKI;KATAYAMA, NOZOMU;KAKIMOTO, SHIGEYA |