Derivatives of the 6-arylpyrido[2,3-d]pyrimidines and naphthyridines, pharmaceutical composition on base thereof, methods of treatment and inhibition of the tyrosine kinaze receptor celle proliferation and migration

摘要

The invention relates to chemistry and medicine, in particular to the protein kinase inhibition. There are claimed derivatives of the 6-arylpyrido[2,3-d]pyrimidines and naphthyridines of formula (I) wherein X represents CH or NB represents halogen, hydroxyl or NR3R4.There are also claimed a pharmaceutical composition and methods of treatment of atherosclerosis, restenosis, psoriasis, bacterial infections and of inhibition of the tyrosine kinase receptor celle proliferation and migration .Claims: 55