| 摘要 |
Compounds having sPLA2 inhibitory effect represented by general formula (I), prodrugs thereof, pharmaceutically acceptable salts thereof or solvates of the same, and sPLA2 inhibitors containing the same as the active ingredient, wherein R<1> represents -(L<1>)-R<6> (wherein L<1> represents a divalent linking group having 1 to 18 atoms, etc.; and R<6> represents a carbon ring having one or more non-interfering substituents, etc.); R<2> represents C1-3 alkyl, etc.; R<3> represents -(L<2>)-(acidic group); R<4> and R<5> represent each hydrogen, a non-interfering substituent, a carbon ring, etc.; Xs independently represent each oxygen or sulfur; and R<A> represents -C(=X)-C(=X)-NH2, etc. |
