| 摘要 |
1. An orally or parenterally administrable composition comprising in admixture L-carnitine, acetyl L-carnitine and propionyl-L-carnitine or the pharmacologically acceptable salt thereof. 2. The composition of Claim 1 as a medicine for suppressing withdrawal symptoms and the craving for alcohol in alcoholics. 3. The composition of Claim 1 as dietary supplement or food products for preventing the abuse of alcohol in substantially healthy subjects. 4. The composition of Claim 1, 2 or 3 wherein the molar ratio L-carnitine:acetyl-L-carnitine:propionyl-L-carnitine or the pharmacologically acceptable salts thereof ranges from 6:4:1 to 3:2:1. 5. The composition of Claim 4 wherein said ratio is 5:4:1. 6. The composition of Claim 4 or 5 in unit dosage form comprising from 0.44 to 0.66 g L-carnitine inner salt; 0.44 to 0.66 g of acetyl L-carnitine inner salt; and from 0.12 to 0.18 g of propionyl-L-carnitine inner salt or equimolar amounts of the pharmacologically acceptable salts thereof. 7. The composition of any of preceding Claims wherein the pharmacologically acceptable salt of L-carnitine, acetyl-L-carnitine and propionyl-L-carnitine is selected from group comprising: chloride; bromide; iodide; aspartate, particularly acid aspartate; citrate, particularly acid citrate; tartrate; phosphate, particularly acid phosphate, fumarate particularly acid fumarate; glycerophosphate; glucose phosphate, lactate; maleate, particularly acid maleate; orotate; oxalate, particularly acid oxalate; sulphate, particularly acid sulphate; trichloroacetate, trifluoroacetate and methanesulphonate. 8. The composition of any of preceding Claims further including food supplements, vitamins, co-enzymes and mineral substances. 9. The use of composition of Claim 1 for producing a medicine suppressing withdrawal symptoms and the craving for alcohol in alcoholics. 10. The use of composition of Claim 1 for producing a food products for preventing the abuse of alcohol in substantially healthy individuals. 11. The method of Claim 9 or 10 wherein the molar ratio L-carnitine:acetyl-L-carnitine:propionyl-L-carnitine or the pharmacologically acceptable salts thereof ranges from 6:4:1 to 3:2:1. 12. The method of Claim 11, wherein the molar ratio is 5:4:1. |
