| 发明名称 |
NEW DIBENZOAZULENE COMPOUNDS AS TUMOR NECROSIS FACTOR INHIBITORS |
| 摘要 |
The present invention relates to the dibenzoazulene compounds represented by formula I as well as to their pharmaceutical preparations for the inhibition of tumor necrosis factor alpha (TNF-alpha) and interleukine 1 (IL-1) in mammals at all diseases and conditions where these mediators are excessively secreted. The compounds of the present invention also demonstrate an analgetic action and can be used to relieve pain. |
| 申请公布号 |
HRP20000310(A2) |
申请公布日期 |
2002.02.28 |
| 申请号 |
HR2000P000310 |
申请日期 |
2000.05.17 |
| 申请人 |
PLIVA D.D. |
发明人 |
MLADEN MERµEP;MILAN MESIµ;DIJANA PEUEIµ;AEELJKO AEUPANOVIµ;BOUEKA HRVAÞIµ |
| 分类号 |
A61K31/381;A61K31/55;A61P1/04;A61P11/06;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P27/02;A61P29/00;A61P35/00;A61P37/02;A61P43/00;C07B61/00;C07D495/04 |
主分类号 |
A61K31/381 |
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