发明名称 METHODS OF DRUG DELIVERY TO HEPATOCYTES AND TREATMENT OF FLAVIVIRIDAE INFECTIONS
摘要 A method of delivering a drug to a hepatocyte includes a step in which a carboxamidine group-containing compound is provided to a hepatocyte having a transporter that transports the compound across the plasma membrane of the hepatocyte, wherein the transport of the compound is substantially not inhibited by ribavirin. Further contemplated methods include a method of inhibiting growth of a virus of a family of flaviviridae in a cell containin g system, in which contemplated compounds are presented to a cell in the cell containing system.
申请公布号 CA2415793(A1) 申请公布日期 2002.02.28
申请号 CA20012415793 申请日期 2001.08.21
申请人 RIBAPHARM INC. 发明人 HONG, ZHI;LAU, JOHNSON
分类号 C12N7/06;A61K31/155;A61K31/41;A61K31/7056;A61P1/16;A61P31/12;A61P31/14;A61P35/00;C07H19/056;(IPC1-7):A61K31/41 主分类号 C12N7/06
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