发明名称
摘要 Modified amino acid compounds useful for the delivery of active agents are provided. The amino acids, non-alpha-amino acids, have been modified by acylation on the amino group particularly with phenyl or cyclohexyl groups. These groups have a variety of substituents including but not limited to hydroxy, methyl, fluoro, chloro, and the like. The compounds of the invention can be combined with numerous active agents including but not limited to heparin, peptides, and parathyroid hormone, and can then be used for effective administration of the active agent. Administration can be, for example, oral or parenteral.
申请公布号 JP2002506418(A) 申请公布日期 2002.02.26
申请号 JP19960529751 申请日期 1996.04.01
申请人 发明人
分类号 C07D295/20;A61K9/00;A61K9/08;A61K9/16;A61K9/20;A61K9/48;A61K31/197;A61K31/198;A61K31/40;A61K31/44;A61K38/00;A61K38/04;A61K38/11;A61K38/21;A61K38/22;A61K38/23;A61K38/27;A61K38/28;A61K38/29;A61K39/00;A61K39/395;A61K45/00;A61K47/12;A61K47/16;A61K47/18;A61K47/20;A61K47/22;A61K47/48;C07C53/126;C07C53/134;C07C229/08;C07C229/10;C07C229/42;C07C231/12;C07C233/34;C07C233/47;C07C233/48;C07C233/51;C07C233/52;C07C233/54;C07C233/55;C07C233/63;C07C233/81;C07C233/83;C07C233/84;C07C233/87;C07C235/24;C07C235/34;C07C235/38;C07C235/40;C07C235/52;C07C235/56;C07C235/60;C07C235/62;C07C235/64;C07C235/78;C07C235/82;C07C235/84;C07C237/22;C07C237/40;C07C237/42;C07C239/06;C07C239/08;C07C259/06;C07C271/22;C07C303/22;C07C303/40;C07C309/59;C07C311/19;C07D207/34;C07D207/416;C07D213/75;C07D213/81;C07D295/215;C07D317/68;C07D333/38 主分类号 C07D295/20
代理机构 代理人
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