发明名称 Crystalline or crystallized acid addition salt of losartan and purification method of losartan
摘要 The present invention provides a crystalline or crystallized acid addition salt of Losartan useful for obtaining highly pure 2-n-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol (Losartan), and a purification method of Losartan that includes production of the crystalline or crystallized acid addition salt.
申请公布号 US6350880(B1) 申请公布日期 2002.02.26
申请号 US20000714339 申请日期 2000.11.16
申请人 SUMIKA FINE CHEMICALS CO., LTD. 发明人 KATSURA TADASHI;SHIRATANI HIROSHI;ITAYA NOBUSHIGE
分类号 A61K31/4178;A61P43/00;C07D403/10;(IPC1-7):C07D257/04 主分类号 A61K31/4178
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