发明名称 |
Crystalline or crystallized acid addition salt of losartan and purification method of losartan |
摘要 |
The present invention provides a crystalline or crystallized acid addition salt of Losartan useful for obtaining highly pure 2-n-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol (Losartan), and a purification method of Losartan that includes production of the crystalline or crystallized acid addition salt.
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申请公布号 |
US6350880(B1) |
申请公布日期 |
2002.02.26 |
申请号 |
US20000714339 |
申请日期 |
2000.11.16 |
申请人 |
SUMIKA FINE CHEMICALS CO., LTD. |
发明人 |
KATSURA TADASHI;SHIRATANI HIROSHI;ITAYA NOBUSHIGE |
分类号 |
A61K31/4178;A61P43/00;C07D403/10;(IPC1-7):C07D257/04 |
主分类号 |
A61K31/4178 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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