LARGE AREA SUBMUCOSAL GRAFT CONSTRUCTS AND METHOD FOR MAKINGTHE SAME

摘要

Multi-laminar tissue graft constructs, pseudoisotropic graft constructs and a method of preparing such constructs are described. Multi-laminar tissue graf t constructs are prepared by fusing partially overlapped strips of submucosa tissue into a unitary graft construct by compressing the tissue under dehydrating conditions. Pseudoisotropic tissue graft constructs are prepared by overlapping a first strip of submucosa tissue with at least two strips of submucosa tissue orientated so that the longitudinal axis of each strip form s an angle of about 180~/N with the longitudinal axes of at least two other strips of submucosal tissue.