| 发明名称 |
Alpha7 nicotinic receptor peptides as ligands for beta amyloid p eptides |
| 摘要 |
The present invention describes native and degenerate peptides derived from human alpha7 nicotinic receptor useful as minimized ligands for beta amyloid peptides. These peptides are useful to discover compounds that inhibit the interaction with beta amyloid peptides with the alpha7 nicotinic receptor, and are also useful in assays to measure beta amyloid. |
| 申请公布号 |
AU8126801(A) |
申请公布日期 |
2002.02.25 |
| 申请号 |
AU20010081268 |
申请日期 |
2001.08.14 |
| 申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
DANIEL H. S. LEE;ALLEN B REITZ;CARLOS PLATA-SALAMAN;HOAU-YAN WANG |
| 分类号 |
A61K38/00;A61P25/28;C07K7/06;C07K7/08;C07K14/705;C07K19/00 |
主分类号 |
A61K38/00 |
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