| 摘要 |
The present invention relates to a novel use of bufadienolide derivatives, as such or in the form of pharmaceutical compositions, for immunomodulation, especially for immunosuppression, for antiinflammatory and/or for antitumor action, as especially for the use in the treatment (including therapy and/or prophylaxis) of conditions in warm-blooded animals that are responsive to said actions; to the use of said derivatives for the manufacture of a pharmaceutical preparation for the treatment of a disease or condition that responds to said actions; to processes for the manufacture of pharmaceutical compositions for this novel use; to pharmaceutical compositions comprising the steroids and/or to a method of treatment comprising administering such a steroid; the invention also relates to novel steroids of that type, to those novel compounds for use in a method for the diagnostic or therapeutic treatment of the human or animal body, and to processes for the preparation of these compounds and to novel intermediates useful for their preparation. |
