发明名称 Granulation process and starch granulate
摘要 A process for the manufacture of a corn starch granulate possessing resistance to enzymatic degradation upon oral administration, comprising the steps: a) granulating native corn starch by cautious mixing of a granulation fluid comprising a binder ethanol or water as a solvent, corn starch and a sweetener; b) subjecting the granulated material resulting from step a) to wet sieving; c) drying the granulate obtained in step b) at a temperature less than about 55° C. to avoid gelatinization of the corn starch; and d) sizing the dried granulate from step c) by dry sieving; and a corn starch granulate comprising primary corn starch granules as they appear in untreated native corn starch, said primary granules being agglomerated, without degradation thereof, into larger secondary granules to form a granulate using a binder selected from pre-gelatinized corn starch, gum arabicum, guar gum, potassium alginate, carageenan, methyl cellulose, and ethyl cellulose.
申请公布号 SE0200539(D0) 申请公布日期 2002.02.25
申请号 SE20020000539 申请日期 2002.02.25
申请人 METCON MEDICIN AB 发明人 HENRI *HANSSON;ELISABETH *LINDNER-OLSSON
分类号 A61K9/16;A61K9/20;(IPC1-7):A61J/ 主分类号 A61K9/16
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