发明名称 |
PROLINE DERIVATIVES AND USE THEREOF AS DRUGS |
摘要 |
The invention aims at providing compounds which exhibit therapeutic effects through the inhibition of DPP-IV and are satisfactory as drugs. The inventio n has been accomplished by finding that .gamma.-substituted proline derivative s of the general formula (I) exhibit potent DPP-IV inhibitory activities and improving the same in stability. [In the general formula, each symbol is as defined in the description.]
|
申请公布号 |
CA2418656(A1) |
申请公布日期 |
2002.02.21 |
申请号 |
CA20012418656 |
申请日期 |
2001.08.10 |
申请人 |
MITSUBISHI PHARMA CORPORATION |
发明人 |
HAYASHI, YOSHIHARU;AKAHOSHI, FUMIHIKO;SAKASHITA, HIROSHI;KITAJIMA, HIROSHI |
分类号 |
A61P1/02;A61P3/04;A61P3/10;A61P13/08;A61P17/00;A61P31/18;A61P35/04;A61P37/06;A61P43/00;C07D207/16;C07D401/14;C07D403/14;C07D413/14;C07D417/06;C07D417/14;C07D471/10;C07D487/04;C07D498/04;(IPC1-7):C07D207/16;A61K31/401;A61K31/427;A61K31/438;A61K31/443;A61K31/454;A61K31/470;A61K31/496;A61K31/502;A61K31/506;A61K31/517;A61K31/537;A61K31/551 |
主分类号 |
A61P1/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|