发明名称 |
Reverse-turn mimetics and methods relating thereto |
摘要 |
Conformationally constrained compounds which mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetics have utility in the treatment of cell adhesion-indicated diseases, such as multiple sclerosis, atherosclerosis, asthma and inflammatory bowel disease.
|
申请公布号 |
US2002022620(A1) |
申请公布日期 |
2002.02.21 |
申请号 |
US20000742680 |
申请日期 |
2000.12.19 |
申请人 |
KAHN MICHAEL;EGUCHI MASAKATSU;KIM HWA-OK;STASIAK MARCIN |
发明人 |
KAHN MICHAEL;EGUCHI MASAKATSU;KIM HWA-OK;STASIAK MARCIN |
分类号 |
A61K31/4985;A61K31/517;A61K31/519;A61K31/551;A61K38/00;A61P1/00;A61P3/10;A61P9/00;A61P9/08;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P25/00;A61P25/28;A61P27/02;A61P29/00;A61P31/18;A61P35/00;A61P37/08;A61P43/00;C07B61/00;C07D487/04;C07D498/04;C07K5/02;C07K5/078;(IPC1-7):A61K31/551;A61K31/498 |
主分类号 |
A61K31/4985 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|