发明名称 DENTAL PRODUCTS COMPRISING BONE GROWTH ENHANCING PEPTIDE
摘要 Dental products such as toothpastes, mouthwash and dental floss are disclose d which products are enhanced by having dissolved, dispersed or coated thereon a compound which promoted bone growth. Preferred compounds are peptide sequenc es comprising 10 to 50 amino acids are disclosed. The sequences are characteriz ed by containing an integrin binding motif such as RGD sequence and the remaind er of amino acids contiguous with the RGD sequence in matrix extracellular phosphoglycoprotein. The sequences may be formulated for dispersed in toothpaste or a mouthwash and administered to enhance bone/tooth growth. Whe n the dental products are used repeatedly over time they enhance good dental health.
申请公布号 CA2417207(A1) 申请公布日期 2002.02.21
申请号 CA20012417207 申请日期 2001.08.09
申请人 ACOLOGIX, INC. 发明人 KUMAGAI, YOSHINARI;NOMIZU, MOTOYOSHI;YONEDA, TOSHIYUKI
分类号 A61K8/00;A61K8/64;A61K38/00;A61K38/16;A61K38/17;A61P1/02;A61Q11/00;C07K7/06;C07K7/08;C07K14/00;C07K17/00;(IPC1-7):A61K7/16;A61K7/22 主分类号 A61K8/00
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