发明名称 |
DENTAL PRODUCTS COMPRISING BONE GROWTH ENHANCING PEPTIDE |
摘要 |
Dental products such as toothpastes, mouthwash and dental floss are disclose d which products are enhanced by having dissolved, dispersed or coated thereon a compound which promoted bone growth. Preferred compounds are peptide sequenc es comprising 10 to 50 amino acids are disclosed. The sequences are characteriz ed by containing an integrin binding motif such as RGD sequence and the remaind er of amino acids contiguous with the RGD sequence in matrix extracellular phosphoglycoprotein. The sequences may be formulated for dispersed in toothpaste or a mouthwash and administered to enhance bone/tooth growth. Whe n the dental products are used repeatedly over time they enhance good dental health.
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申请公布号 |
CA2417207(A1) |
申请公布日期 |
2002.02.21 |
申请号 |
CA20012417207 |
申请日期 |
2001.08.09 |
申请人 |
ACOLOGIX, INC. |
发明人 |
KUMAGAI, YOSHINARI;NOMIZU, MOTOYOSHI;YONEDA, TOSHIYUKI |
分类号 |
A61K8/00;A61K8/64;A61K38/00;A61K38/16;A61K38/17;A61P1/02;A61Q11/00;C07K7/06;C07K7/08;C07K14/00;C07K17/00;(IPC1-7):A61K7/16;A61K7/22 |
主分类号 |
A61K8/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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