34P3D7: A TISSUE SPECIFIC PROTEIN HIGHLY EXPRESSED IN PROSTATE CANCER

摘要

A novel gene (designated 34P3D7) and its encoded protein are described. While 34P3D7 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in multiple cancers including prostate, bladder, kidney, brain, bone, cervical, uterine, ovarian, breast, pancreatic, stomach, colon, rectal, leukocytic, liver and lung cancers. Consequently, 34P3D7 provides a diagnostic and/or therapeutic target for cancers, and the 34P3D7 gene or fragment thereof, or its encoded protein or a fragment thereof can be used to elicit an immune response.