发明名称 |
COMPOSITIONS AND METHODS FOR INDUCING ACTIVATION OF DENDRITIC CELLS |
摘要 |
Compositions induce the activation of dendritic cells comprising a polynucleotide, such as viruses, RNA, DNA, plasmid DNA, or derivatives thereof and at least one block copolymer of alkylethers. The present invention further relates to compositions for inducing the activation of dendritic cells wherein the block copolymers are PLURONIC F127 and L61. More particularly, the compositions comprise block copolymers PLURONIC F127/PLURONIC L61. The invention also relates to methods of inducing the activation of dendritic cells in animals comprising administering the compositions of the invention. Additionally, the present invention relates to methods of increasing the immune response of animals comprising administering the compositions of the present invention. |
申请公布号 |
WO0183698(A3) |
申请公布日期 |
2002.02.21 |
申请号 |
WO2001US13921 |
申请日期 |
2001.04.30 |
申请人 |
SUPRATEK PHARMA, INC.;KABANOV, ALEXANDER V.;LEMIEUX, PIERRE;GUERIN, NADIA;ALAKHOV, VALERY;VINOGRADOV, SERGUIE |
发明人 |
KABANOV, ALEXANDER V.;LEMIEUX, PIERRE;GUERIN, NADIA;ALAKHOV, VALERY;VINOGRADOV, SERGUIE |
分类号 |
A61K9/08;A61K9/10;A61K9/107;A61K31/765;A61K31/785;A61K35/76;A61K38/00;A61K39/00;A61K39/39;A61K45/06;A61K47/34;A61K47/48;A61K48/00;A61P1/16;A61P9/10;A61P29/00;A61P31/12;A61P31/18;A61P31/22;A61P35/00;A61P37/04;A61P37/06;A61P43/00;C12N15/113 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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