| 发明名称 |
Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade |
| 摘要 |
The invention relates to polycyclic aryl and heteroaryl substituted 4-pyrone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
|
| 申请公布号 |
US2002022604(A1) |
申请公布日期 |
2002.02.21 |
| 申请号 |
US20010826432 |
申请日期 |
2001.04.04 |
| 申请人 |
SOUTH MICHAEL S.;MA CHUN C.;KOELLER KEVIN J.;RAHMAN HAYAT K.;NEUMANN WILLIAM L. |
发明人 |
SOUTH MICHAEL S.;MA CHUN C.;KOELLER KEVIN J.;RAHMAN HAYAT K.;NEUMANN WILLIAM L. |
| 分类号 |
A61K31/351;A61P7/02;A61P9/10;A61P43/00;C07D309/38;C07D309/40;C07D405/12;(IPC1-7):A61K31/502;A61K31/506;A61K31/501;A61K31/470;A61K31/472;A61K31/422;A61K31/675 |
主分类号 |
A61K31/351 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
