发明名称 |
AMINO ACID-DERIVED PHOSPHONAMIDIC ANHYDRIDES AND METHODS OF PREPARING THE SAME |
摘要 |
New phosphonamide compounds and methods of forming those compounds are provided. The inventive methods comprise forming a template opened-ring phosphonamide compound and optionally subjecting the template to a ring-closing metathesis reaction in the presence of a ring-closing catalyst (e.g., a Grubbs catalyst) to yield a heterocyclic phosphonamide. Advantageously, the template structures can be provided with a wide array of functional groups (e.g., amino acid side chains, peptides) chosen to provide particular properties to the compound. The preferred heterocyclic phosphonamides are represented by formula (I).
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申请公布号 |
WO0214331(A1) |
申请公布日期 |
2002.02.21 |
申请号 |
WO2001US41602 |
申请日期 |
2001.08.06 |
申请人 |
THE UNIVERSITY OF KANSAS |
发明人 |
SPROTT, KEVIN, T.;HANSON, PAUL, R. |
分类号 |
C07F9/44;C07F9/6584;(IPC1-7):C07F9/553;C07F9/572;C07F9/22;C07F9/06;C07F9/02 |
主分类号 |
C07F9/44 |
代理机构 |
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主权项 |
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