NOVEL PROTEIN

摘要

A method for the identification of a compound which modulates leukotriene B4 like (LTRGW1) receptor activity comprises contacting an LTRGW1 polypeptide comprisingi) The amino acid sequence of SEQ ID #2, or ii) A variant of (i) which is capable of binding leukotrienes; oriii) A fragment of (i) or (ii) which is capable of binding leukotrienes. Additionally, LTRGW1 has been determined to enhance the response of the leukotriene B4 Receptor (BLTR) to LTB4. Hence LTRGW1 may be used in methods to indentify compounds which modulate BLTR receptor activity.