发明名称 |
12303, A NOVEL HUMAN TWIK MOLECULE AND USES THEREOF |
摘要 |
The invention provides isolated nucleic acids molecules, designated TWIK-8 nucleic acid molecules, which encode novel TWIK-related potassium channel subunit molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing TWIK-8 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a TWIK-8 gene has been introduced or disrupted. The invention still further provides isolated TWIK-8 proteins, fusion proteins, antigenic peptides and anti-TWIK-8 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
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申请公布号 |
WO0177329(A8) |
申请公布日期 |
2002.02.21 |
申请号 |
WO2001US11301 |
申请日期 |
2001.04.06 |
申请人 |
MILLENIUM PHARMACEUTICALS, INC.;GLUCKSMANN, MARIA, ALEXANDRA |
发明人 |
GLUCKSMANN, MARIA, ALEXANDRA |
分类号 |
A61K38/00;C07K14/705;C12N15/12;(IPC1-7):C12N15/12;C12N5/10;C07K14/47;C07K16/18;C12Q1/68 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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