PHARMACEUTICAL COMPOSITIONS CONTAINING DERIVATIVES OF ESTRA-1,3,5(10)-TRIENE

摘要

medicine, pharmacy. SUBSTANCE: invention proposes pharmaceutical compositions containing derivatives of estra-1,3,5(10)-triene as active components which carry in their C3 position the group of the general formula R-SO2- O- where R means the group R1R2N where R1 and R2 mean oxygen atom independently each of other, C1-C5-alkyl radical or in common with nitrogen atom they mean polymethyleneimino-group containing 4-6 carbon atoms or morpholino-group. Compositions are designated for hormonal contraception and hormone substitution therapy and they elicite low estrogen activity with respect to liver. EFFECT: valuable medicinal properties of compositions. 3 cl, 10 tbl, 10 ex