发明名称 2-phenyl benzimidazole derivatives as MCP-1 antagonists
摘要 Benzimidazole derivatives of Formula I or a pharmaceutically acceptable salt thereof are MCP-1 antagonists and are thus useful in the treatment of inflammation, atherosclerosis, restenosis, and immune disorderswherein A is N or CH;where W, X, Y, and Z can be independently C-R2, C-R3, C-R4, C-R5, or N;no more than two of W, X, Y, and Z can be N in any one structure,R2, R3, R4, and R5 are as define in the specification.
申请公布号 US6348487(B1) 申请公布日期 2002.02.19
申请号 US20000698342 申请日期 2000.10.27
申请人 MILLENNIUM PHARMACEUTICALS, INC. 发明人 CONNOR DAVID THOMAS;GLASE SHELLY ANN;PURCHASE TERRI STOEBER;ROTH BRUCE DAVID;TRIVEDI BHARAT KALIDAS
分类号 A61K31/4184;A61K31/437;A61K31/454;A61K31/52;A61P9/10;A61P17/00;A61P29/00;A61P37/00;C07D209/14;C07D235/02;C07D235/18;C07D471/04;C07D473/00;(IPC1-7):A61K31/405 主分类号 A61K31/4184
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