| 发明名称 |
NPY antagonists: spiroisoquinolinone derivatives |
| 摘要 |
A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of spiroisoquinolinone derivatives of Formula I.As antagonists of NPY-induced feeding behavior, these compounds and known analogs are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.
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| 申请公布号 |
US6348472(B1) |
申请公布日期 |
2002.02.19 |
| 申请号 |
US20000586146 |
申请日期 |
2000.06.02 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
POINDEXTER GRAHAM S.;ANTAL ILDIKO;GIUPPONI LEAH M.;STOFFEL ROBERT H.;BRUCE MARC A. |
| 分类号 |
A61K31/4747;A61P1/00;A61P1/04;A61P3/04;A61P3/10;A61P5/00;A61P7/12;A61P9/00;A61P11/06;A61P13/12;A61P25/00;A61P25/08;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P29/00;A61P43/00;C07D471/10;(IPC1-7):C07D471/10;A61K31/438 |
主分类号 |
A61K31/4747 |
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