发明名称 |
Soluble zcytor 11 cytokine receptors |
摘要 |
There is provided the use of an antagonist of IL-TIF activity in the manufacture of a medicament for treating an inflammatory or immune disease in a mammal, wherein said antagonist is an antibody that specifically binds to a heterodimeric receptor complex having a first receptor subunit consisting of a zcytoR11 polypeptide as shown in SEQ ID NO:3 and a second receptor subunit consisting of a CRF2-4 receptor polypeptide as shown in SEQ ID NO:33. |
申请公布号 |
AU9052401(A) |
申请公布日期 |
2002.02.18 |
申请号 |
AU20010090524 |
申请日期 |
2001.08.08 |
申请人 |
ZYMOGENETICS INC. |
发明人 |
WAYNE R. KINDSVOGEL;STAVROS TOPOUZIS |
分类号 |
C12N15/09;A61K38/00;A61P29/00;A61P37/00;A61P37/02;A61P37/06;C07K14/715;C07K16/28;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/02;C12P21/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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