发明名称 |
4-pyrimidinamine derivatives, pharmaceutical compositions and related methods |
摘要 |
This invention provides novel neuroprotective 4-pyrimidineamine derivatives and neuroprotective pharmaceutical compositions comprising 4-pyrimidinamines. This invention also provides methods of using these compositions to prevent ischemic cell death, particularly neuronal cell death, and reduce the likelihood of neuronal cell death in a subject due to a traumatic event. Finally, this invention provides an apparatus for administering to a subject the instant pharmaceutical compositions. |
申请公布号 |
AU8112001(A) |
申请公布日期 |
2002.02.18 |
申请号 |
AU20010081120 |
申请日期 |
2001.08.06 |
申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
ELFRIDA R. GRANT;FRANK K. BROWN;ROBERT ALLAN ZIVIN;MICHAEL MCMILLAN;ZHONG ZHONG;MALCOLM SCOTT;ALLEN B REITZ;TINA MORGAN ROSS |
分类号 |
A61K31/505;A61K31/506;A61K31/5377;A61K31/55;A61P25/00;A61P25/28;A61P43/00;C07D239/12;C07D239/42;C07D239/52;C07D239/54;C07D401/12;C07D401/14;C07D403/12;C07D405/04;C07D405/12;C07D409/04;C07D495/04 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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