| 摘要 |
<p>Industrial preparation of sodium orthohydroxymandelate comprises condensing phenol with aqueous glyoxylic acid under inert atmosphere in presence of a tertiary amine and catalytic trivalent metallic cations at < 100 degrees C. The process is carried out in a continuous way in two reaction vessels (R1, Rn) connected in series. The first one is fed by a container (C1) comprising of glyoxylic acid and trivalent metallic cations and the outlet of the two reactors consisting of an aqueous phase and an organic phase is transferred to the first of the two mixers (MD1, MD2) connected in series. The aqueous phase from the first mixer is collected and sodium orthohydroxymandelate is then extracted. The organic phase from the first mixer is transferred to the second mixer where it is washed. The organic phase from the second mixer is transferred to container (C2).</p> |
