发明名称 LACTIC ACID POLYMER AND PROCESS FOR PRODUCING THE SAME
摘要 A process for producing a lactic acid polymer which has a weight-average molecular weight of 15,000 to 50,000 and in which the content of polymeric components having a weight-average molecular weight of about 5,000 or lower is about 5 wt.% or lower, characterized by hydrolyzing a high-molecular lactic acid polymer, allowing the resultant solution containing the hydrolyzates to stand under such conditions that the target lactic acid polymer contained therein can precipitate, and isolating the precipitate. The lactic acid polymer is useful as a base for sustained-release drugs which sufficiently inhibits microcapsules containing a physiologically active substance from excesssively releasing the physiologically active substance in an initial stage and can stably maintain a rate of its release over long.
申请公布号 WO0212369(A1) 申请公布日期 2002.02.14
申请号 WO2001JP06721 申请日期 2001.08.06
申请人 WAKO PURE CHEMICAL INDUSTRIES, LTD.;TAKEDA CHEMICAL INDUSTRIES, LTD.;YAMAMOTO, KOHEI;TANI, TSUTOMU;AOKI, TAKASHI;HATA, YOSHIO 发明人 YAMAMOTO, KOHEI;TANI, TSUTOMU;AOKI, TAKASHI;HATA, YOSHIO
分类号 A61K9/16;A61K9/50;A61K9/52;C08G63/08;C08G63/88;C08G63/91;(IPC1-7):C08G63/88;A61K47/34 主分类号 A61K9/16
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