METHODS FOR USING 14266, A HUMAN G PROTEIN-COUPLED RECEPTOR

摘要

The present invention relates to methods for using a human G protein-coupled receptor (14266) belonging to the family of mammalian G protein-coupled receptors. The invention also relates to methods for using polynucleotides encoding the 14266 receptor. The invention relates to methods for detecting the presence of a 14266 polypeptide of a 14266 polynucleotide and kits comprising reagents for detecting the presence of a 14266 polypeptide or polynucleotide. The invention further relates to methods of modulating the level or activity of a 14266 polypeptide in a cell. The invention further relates to drug-screening methods using the 14266 polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the 14266 polypeptides and polynucleotides. The invention further relates to agonists and antagonists identified by drug screening methods with the 14266 polypeptides and polynucleotides as a target.